What the label states, the lot delivers — net peptide mass, not gross powder weight, purity reported as measured rather than rounded up, and a Certificate of Analysis for every lot.
Net peptide mass, not powder weight; purity as measured, not rounded up; a COA per lot.
Net peptide + purity not rounded up. COA per lot.
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FDA PCAC reviews 7 peptides for the 503A bulks list in July. Read →
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Pal-KTTKS matrikine · collagen-signal cosmetic peptide
Overview
Matrixyl is the trade name introduced in 2000 by the French company Sederma SAS. Its active ingredient is Palmitoyl Pentapeptide-4 (called Palmitoyl Pentapeptide-3 before the INCI naming standard was corrected in 2006), chemically a palmitic acid (16-carbon fatty acid) chain conjugated to the pentapeptide Lys-Thr-Thr-Lys-Ser (KTTKS), commonly abbreviated Pal-KTTKS. This pentapeptide sequence is a natural degradation fragment of type I procollagen (a matrikine, or matrix-derived signal peptide); palmitoylation was added to improve lipophilicity, skin stability, and transdermal penetration. Vialdyne releases Matrixyl as a lyophilized peptide against a ≥98% HPLC main-peak specification, supplied with a batch-specific Certificate of Analysis covering RP-HPLC purity, mass-spec identity, appearance, and water content. Lots are released only after the COA is on file.
Applications & buyer fit
Cosmetic-peptide buyers fall into two groups: established beauty / med-aesthetic brands extending an existing line, and OEM clients building a private-label catalog from scratch. The first group usually wants active material plus stability data in their existing carrier matrix; the second usually wants a finished formulation under their label. Both need INCI naming verified, regulator-specific safety files (CPNP for EU, FDA OTC monograph for US where relevant), and packaging-compatibility data.
Sourced for
Buyer fit
Documentation that ships
Procurement note: INCI naming, SDS, and stability data in the chosen carrier ship with the active; finished-product safety remains the brand owner's responsibility.
Primary buyer fit: academic and contract research laboratories.
Specifications
Certificate of Analysis
Published released-batch COAs for Matrixyl, every lot HPLC-verified. These are previews — request the full high-resolution certificate for any lot.
Browse all published COAsRegulatory note
Research-use-only reference material; not for human or veterinary use.
Selected literature
Frequently asked questions
Matrixyl ships as white to off-white lyophilized powder with a batch-specific Certificate of Analysis reporting RP-HPLC purity (≥98%), mass-spec identity and sequence Pal-Lys-Thr-Thr-Lys-Ser, and appearance. Recommended storage: 2–8°C. Supplied strictly as a research reference material — not for human or veterinary use.
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