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Off-spec? Free replacement or full refund.
FDA PCAC reviews 7 peptides for the 503A bulks list (BPC-157, KPV, TB-500, MOTs-C, Emideltide, Semax, Epitalon). Read our compounder's decision tree. Read our briefing →
FDA PCAC reviews 7 peptides for the 503A bulks list in July. Read →
FDA PCAC: 7 peptides under review. Read →
Pineal tetrapeptide · telomere research
Overview
Epitalon (also spelled Epithalon) is a synthetic tetrapeptide, Ala-Glu-Asp-Gly, modelled on the active fragment of the pineal polypeptide preparation Epithalamin characterised by Khavinson. It is one of the most-cited longevity research peptides, studied for its reported effects on telomerase expression, telomere maintenance, and circadian/melatonin regulation in cell and animal models. Vialdyne releases lyophilised Epitalon to a ≥99.0% HPLC main-peak specification, with a batch COA available from sales. Every released lot comes with its batch COA covering RP-HPLC purity and mass-spec identity; peptide-content assay, related substances, water (Karl Fischer), acetic-acid counter-ion, residual solvents and endotoxin are available on request and listed on the COA when tested. Sequence and ESI-MS identity are documented on the same lot for reference-standard qualification.
Applications & buyer fit
Buyers for longevity-class peptides span research labs working on telomere, collagen, and circadian-rhythm models, plus cosmetic-formulation OEMs incorporating peptides like GHK-Cu into anti-aging finished products. Copper peptides in particular require attention to chelator-free water and EDTA-free buffers in downstream formulation work, incompatibility there is the most common cause of "the peptide didn't work" support tickets in this class.
Sourced for
Buyer fit
Documentation that ships
Procurement note: Copper peptides require chelator-free water and EDTA-free buffers in downstream formulation work.
Primary buyer fit: academic and contract research laboratories.
Specifications
Nasal spray listing · US inventory
Epithalon is also listed in this catalog as a nasal spray solution.

Batch COAs and test reports
Each picture is a low-resolution preview of a report's first page, with batch and report numbers covered. For the full, clear report, ask our sales team, naming the product and strength.
Batch COAEpithalon 10 mg
HPLC purity · MS identity
Batch COA
Full, clear copy from sales
Batch COAEpithalon 50 mg
HPLC purity · MS identity
Batch COA
Full, clear copy from sales
Third-party reportEpithalon 50 mg
HPLC purity · MS identity
Third-party laboratory, Tianjin, China
Full, clear copy from sales
Independent test fails? Full refund. How it works
Browse all COAs and reportsRegulatory note
Research-use-only reference material; not an approved drug in the US or EU. Not for human or veterinary use.
Frequently asked questions
Yes, they are two transliterations of the same synthetic tetrapeptide, Ala-Glu-Asp-Gly (CAS 307297-39-8). It is the short synthetic peptide modelled on Epithalamin, the natural pineal polypeptide complex studied by Khavinson and colleagues. The COA lists the sequence and ESI-MS identity so spelling differences across suppliers can be reconciled to one molecule.
Research interest centres on reports that Epitalon can induce telomerase activity and support telomere maintenance in somatic cells, alongside effects on melatonin and circadian regulation attributed to its pineal origin. These are research findings in cell and animal models; Vialdyne supplies the peptide strictly as a research reference material and makes no therapeutic claim.
Yes. Epithalon is listed as a nasal spray solution (10 mg), filled in 10 mL or 20 mL bottles, with an MOQ of 10 bottles per content and fill. It is dispatched within the United States from US inventory; send an inquiry for current availability.
Send any vial from your order to an independent laboratory of your choice. If the report shows the product does not meet the specification on its COA — purity below the stated minimum, or an identity that does not match — share the report with our sales team and we refund that product in full.
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