What the label states, the lot delivers — net peptide mass, not gross powder weight, purity reported as measured rather than rounded up, and a Certificate of Analysis for every lot.
Net peptide mass, not powder weight; purity as measured, not rounded up; a COA per lot.
Net peptide + purity not rounded up. COA per lot.
FDA PCAC reviews 7 peptides for the 503A bulks list (BPC-157, KPV, TB-500, MOTs-C, Emideltide, Semax, Epitalon). Read our compounder's decision tree. Read our briefing →
FDA PCAC reviews 7 peptides for the 503A bulks list in July. Read →
FDA PCAC: 7 peptides under review. Read →
Fatty-acid-transport small-molecule reference standard
Overview
L-Carnitine (Levocarnitine) is a naturally occurring amino acid derivative that serves as the key shuttle transporting long-chain fatty acids into mitochondria for beta-oxidation. It is endogenously synthesized from lysine and methionine and plays an especially important role in high energy-demand tissues such as the heart, brain, and skeletal muscle. It is FDA-approved (brand name Carnitor®) for treating primary/secondary carnitine deficiency and for carnitine supplementation in hemodialysis patients (the approved injectable formulation is for intravenous use only). Common derivative forms include Acetyl-L-Carnitine (ALCAR, more cognitive-support oriented), L-Carnitine L-Tartrate (LCLT, more exercise-recovery oriented), and Propionyl-L-Carnitine (more cardiovascular-health oriented). Over 200 clinical trials have examined its effects on weight management, exercise performance, cardiac health, cognitive function, and male fertility. Vialdyne releases L-Carnitine as a lyophilized small molecule (quaternary ammonium compound) against a ≥ 99.0% HPLC main-peak specification, with a batch-specific Certificate of Analysis covering RP-HPLC purity, mass-spec identity, water content, residual solvents, and endotoxin. Sequence / identity confirmation is documented on the released lot.
Applications & buyer fit
Mitochondrial-targeted peptides ship primarily to research labs studying OXPHOS, ROS biology, and mitochondrial dysfunction in disease models. The lipophilic / cationic character that drives mitochondrial accumulation also makes these peptides somewhat oxidation-prone in solution, working stocks should be prepared fresh or held at -80 °C rather than -20 °C when the workflow permits.
Sourced for
Buyer fit
Documentation that ships
Procurement note: The cationic / lipophilic character makes these peptides oxidation-prone in solution; working stocks are best held cold and prepared fresh.
Primary buyer fit: academic and contract research laboratories.
Specifications
Regulatory note
Research-use-only reference material; not for human or veterinary use.
Selected literature
Frequently asked questions
Its quaternary-ammonium, zwitterionic structure dictates the methods: HILIC or ion-exchange HPLC for chemical purity (reverse-phase is ineffective without modification), mass-spec at 161 Da for the molecular ion, and chiral HPLC or polarimetry to confirm the L-enantiomer. D-carnitine is the biologically inactive enantiomer and should not be present in reference-grade material, so the chiral check is part of the release packet rather than an optional add-on.
Peprimo supplies the free-base L-Carnitine by default. Acetyl-L-Carnitine (ALCAR) adds an acetyl group at the carnitine nitrogen and crosses the blood-brain barrier more readily — the form used in cognitive and neurological reference work — while L-Carnitine L-Tartrate is a co-crystal with better solid-state stability than the hygroscopic free base. ALCAR and L-Tartrate forms are available on request; specify the form at order placement since they are not interchangeable as standards.
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