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0.6% acetic acid reconstitution diluent
Batch documentation
Ask sales for the Acetic Acid Water COA matched to the offered batch. Review the recorded tests, specifications, and results against your QA and destination-market requirements before quotation.
Overview
Acetic Acid Water is the catalogue's acidic-pH reconstitution diluent: acetic acid diluted to 0.6% in water and filled into sterile vials, ready to use as supplied rather than prepared in the receiving pharmacy. It exists because a subset of peptides will not behave in a neutral diluent. IGF-1 LR3 is the canonical example, mild acidification holds the protein in monomer form and avoids the aggregation that can occur at neutral pH on dilute reconstitution, and several other solubility-limited actives carry the same instruction on their own product pages. Reaching for a dilute acidic water instead of saline or plain water is therefore a per-SKU decision driven by the compound's documented solubility and stability data, not a general-purpose substitution. Vialdyne supplies the 0.6% dilution in 3 ml and 10 ml sterile vials, sized to match the reconstitution volumes those workflows actually use rather than to be decanted from a bulk bottle. Because the strength is what makes the product fit for purpose, the acceptance question for a receiving quality system is narrow: the release documentation should tie a named lot to acetic-acid content at the labelled 0.6%, pH, sterility, bacterial endotoxin at the injectable limit, particulate matter, the fill volume, and the assigned expiry. Buyers who need a different strength (0.1%, 0.3%, and 1.0% are the usual custom asks) should raise it at the quotation stage rather than adjusting a filled vial in-house, since re-diluting a released sterile presentation moves both the strength control and the sterility assurance onto the pharmacy's own record. Selection between diluents follows the same three-way branch documented on the Sterile Water and BAC Water pages: acidic-pH peptides route here, preservative-incompatible peptides route to SWFI under single-use prep, and preservative-compatible multi-dose workflows route to BAC Water.
Applications & buyer fit
Custom-blend buyers are almost always OEM clients building a branded product around a specific ratio of two or more peptides. The development workflow is collaborative: ratio target, analytical method to verify it, stability protocol in the chosen carrier, and packaging selection are all defined in the OEM brief before the first commercial run. Sample-stage volumes are usually 5-10 g of finished blend; commercial MOQ depends on the components.
Sourced for
Buyer fit
Documentation that ships
Procurement note: Ratio target, the analytical method to verify it, stability protocol, and packaging are defined in the OEM brief before the first commercial run.
Primary buyer fit: academic and contract research laboratories, 503A / 503B compounding pharmacies, and regional distributors and re-sellers.
Specifications
Certificate of Analysis
Representative COA previews for Acetic Acid Water; request the certificate matched to the offered or supplied lot from sales. These are previews — request the full high-resolution certificate for any lot.
VerifiedRequest full COA →Acetic Acid Water
VD260428-AA003
VerifiedRequest full COA →Acetic Acid Water
VD260428-AA002
Regulatory note
An acidic-pH reconstitution diluent supplied at a fixed 0.6% dilution. Confirm that sterility, pyrogen (LAL), pH, and injectable-grade status meet the regulations of your target market, and confirm per SKU that the receiving peptide is specified for an acidic diluent before substituting it for water or saline.
Frequently asked questions
The controlling reference is the compound's own documented solubility and stability data, not a house default. A dilute acidic water is indicated where the peptide is poorly soluble at neutral pH or where mild acidification is what keeps it in monomer form on dilute reconstitution, IGF-1 LR3 being the most frequently cited case in this catalogue. Where the compound is stable and soluble near neutral pH, saline or preservative-free water is the better choice and the added acid buys nothing. Treat the diluent as a per-SKU decision recorded in the formulation file, confirm it on the relevant product page before first use, and note that a working stock prepared in an acidic diluent may still need a downstream carrier, such as a BSA-containing buffer for sub-100 ng/mL cell-culture work, to prevent surface adsorption.
Qualify it as an injectable in its own right rather than as a reagent. The certificate should tie a named lot to acetic-acid content at the labelled 0.6% dilution, pH, sterility, bacterial endotoxin at the injectable limit, and particulate matter, and should state the container-closure format, the fill and overfill, and the assigned expiry. Capture the pharmacopeial monograph the batch was released against, and if the finished preparation is destined for a market outside the US, request the alternate-monograph documentation at the quotation stage so the paperwork you archive matches your jurisdiction's compendial expectation. Because these are small-volume sterile vials without an antimicrobial preservative, your standard operating procedure should also record the in-use window after first entry rather than leaving it to habit.
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